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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYFIP2
All Species:
43.64
Human Site:
Y318
Identified Species:
73.85
UniProt:
Q96F07
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96F07
NP_001032409.2
1278
148399
Y318
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Chimpanzee
Pan troglodytes
XP_001137120
1278
148380
Y318
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Rhesus Macaque
Macaca mulatta
XP_001105005
1359
156392
Y399
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Dog
Lupus familis
XP_536455
1288
149367
Y328
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q5SQX6
1253
145641
Y318
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Rat
Rattus norvegicus
NP_001100987
1253
145239
Y318
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508077
1255
145699
Y318
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Chicken
Gallus gallus
XP_414567
1253
145683
Y318
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Frog
Xenopus laevis
Q6GQD1
1253
145619
Y318
M
Q
I
E
L
A
R
Y
I
E
T
S
A
H
Y
Zebra Danio
Brachydanio rerio
Q90YM8
1253
145156
Y318
M
Q
I
E
L
A
R
Y
I
K
T
S
A
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF87
1291
149242
N317
D
M
Q
I
A
P
F
N
Y
I
K
R
S
K
H
Honey Bee
Apis mellifera
XP_395632
1292
149877
Y319
M
Q
I
A
P
F
N
Y
I
K
R
S
K
H
F
Nematode Worm
Caenorhab. elegans
O44518
1262
144995
F316
G
D
M
Q
I
Q
P
F
A
F
V
R
R
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5S2C3
1283
145467
I313
L
H
L
S
P
A
A
I
L
K
E
L
S
V
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
94
99.1
N.A.
97.9
85.8
N.A.
97.6
97.8
96
84.5
N.A.
62.6
65
51
N.A.
Protein Similarity:
100
100
94
99.2
N.A.
98
92.3
N.A.
97.8
98
97.2
91.6
N.A.
77.3
79.1
69.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
0
53.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
13.3
60
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
79
8
0
8
0
0
0
72
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
72
0
0
0
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
8
0
8
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
79
8
% H
% Ile:
0
0
79
8
8
0
0
8
79
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
79
8
0
8
8
0
% K
% Leu:
8
0
8
0
72
0
0
0
8
0
0
8
0
0
0
% L
% Met:
79
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
79
8
8
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
72
0
0
0
8
15
8
0
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
79
15
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
72
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
8
0
0
0
0
0
79
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _